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Aloe Vera Extract Clinical Study


Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin.

Shimpo K, Ida C, Chihara T, Beppu H, Kaneko T, Kuzuya H.

Fujita Memorial Institute of Pharmacognosy, Fujita Health University, Hisai, Mie 514-1296, Japan. shimpo@fujita-hu.ac.jp

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion. Copyright 2002 John Wiley & Sons, Ltd.

PMID: 12203274 [PubMed - indexed for MEDLINE]



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